Fluoride Toxicity

Melatonin Protection on Mercury Exerted Brain Toxicity in the Rat. Mandava V. Rao, Anshita Purohit Zoology Department, University School of Sciences, Gujarat University, Ahmedabad 380 009, India. Website: www.zoologygujaratuni.org Abstract: Effect of melatonin on the neuro hepatotoxicity perplex on by mercuric chloride was studied. Adult rats were fed orally with ii different doses of mercuric chloride (2mg; 4mg/kg body weight) to try thought toxicity with respect to cerebral cerebral hemisphere, cerebellum, electric-light bulb oblongata regions for 60 eld with and without supplementation of melatonin (5mg/kg body weight) intraperitoneally. The results suggest that the graded doses of mercury elicit the depletion of the enzymatic activities like adenosine triphosphatase, succinate dehydrogenase, phosphorylase, alcalescent phosphatase, acid phosphatase, and neutered glycogen, protein and lipid peroxidation levels in creative nous of cerebral hemisphere, cerebel lum and medulla oblongata of brain affecting their respective functions. line of reasoning glucose and mercury levels increased followed by a reduction in body and organ weights. on the whole these effects seemed to be severe in cerebral hemisphere of brain.

Further touch on indices were to some extent maintained in the brain of animals co-treated with melatonin demonstrate it protective role against mercury exerted neurotoxicity in the rat brain. cornerstone: Mercury is a serious environmental and occupational pollutant with toxic effects in all the liveliness organisms (Berlin, 1987). Primary exposures resu lts ascribable to environmental contaminati! on caused as a result of mining, smelting, abundant industrial and agricultural usage including stirring and ingestion via the forage chain. It enters in the body in contour of chemical forms that argon elemental, inorganic and organic, exhibiting its toxicology characters including neurotoxicity, nephrotoxicity, reproductive toxicity and GI toxicity with ulceration and hemorrhage (Clausen, 1993; Hua et...If you want to observe a effective essay, order it on our website: BestEssayCheap.com

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